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JKFN Journal of the Korean Society of Food Science and Nutrition

Online ISSN 2288-5978 Print ISSN 1226-3311

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Journal of the Korean Society of Food Science and Nutrition 2020; 49(12): 1301-1308

Published online December 31, 2020 https://doi.org/10.3746/jkfn.2020.49.12.1301

Copyright © The Korean Society of Food Science and Nutrition.

Inhibitory Effect of Yacon Leaf Extract on the Metabolic Syndrome Induced by a High Fructose Diet in Rats

Hyun Wook Jang1, So-Yeon Go2, Mi Hyun Hong2, and Young-Eun Lee2,3

1Department of Agrofood Resources, National Institute of Agricultural Science, Rural Development Administration
2Department of Convergence Technology for Food Industry, Wonkwang University
3Wonkwang Research Institute for Food Industry

Correspondence to:Young-Eun Lee, Department of Food and Nutrition, Wonkwang University, Jeonbuk 54538, Korea,
E-mail: yelee@wku.ac.kr
Author information: So-Yeon Go (Researcher), Mi Hyun Hong (Graduate student), Young-Eun Lee (Professor)

Received: October 13, 2020; Accepted: November 28, 2020

Abstract

This study was conducted to investigate the inhibitory effect of 70% ethanol extract of yacon leaf on the metabolic syndrome induced by a high fructose (HF) diet in male Sprague-Dawley (SD) white rats. Five-week-old rats were divided into four groups and the experiment was carried out for 8 weeks. AIN-76A diets were fed to the control group and 60% HF diet to the metabolic syndrome induced group. Yacon leaf extracts were orally administered to the two experimental groups from the 5th week of the HF diet. The HF diet increased body weight, blood pressure, epididymal fat weight and size, total cholesterol, triglyceride, LDL-C, insulin and aorta thickness of the rats, but yacon leaf extracts administration reduced these changes. These results suggest that yacon leaf has an excellent preventive effect on the metabolic syndrome by improving obesity, dyslipidemia and blood pressure induced by an HF diet in rats. Therefore, yacon leaf has the potential for use as an ingredient in novel health foods for the prevention of the metabolic syndrome in the future.

Keywords: yacon leaf, metabolic syndrome, obesity, dyslipidemia, hypertension

Article

Article

Journal of the Korean Society of Food Science and Nutrition 2020; 49(12): 1301-1308

Published online December 31, 2020 https://doi.org/10.3746/jkfn.2020.49.12.1301

Copyright © The Korean Society of Food Science and Nutrition.

고과당식이로 유도된 흰쥐에서 야콘 잎 추출물의 대사증후군 억제 효과

장현욱1․고소연2․홍미현2․이영은2,3

1농촌진흥청 국립농업과학원 농식품자원부
2원광대학교 식품산업융복합학과
3원광식품산업연구원

Received: October 13, 2020; Accepted: November 28, 2020

Inhibitory Effect of Yacon Leaf Extract on the Metabolic Syndrome Induced by a High Fructose Diet in Rats

Hyun Wook Jang1, So-Yeon Go2, Mi Hyun Hong2, and Young-Eun Lee2,3

1Department of Agrofood Resources, National Institute of Agricultural Science, Rural Development Administration
2Department of Convergence Technology for Food Industry, Wonkwang University
3Wonkwang Research Institute for Food Industry

Correspondence to:Young-Eun Lee, Department of Food and Nutrition, Wonkwang University, Jeonbuk 54538, Korea,
E-mail: yelee@wku.ac.kr
Author information: So-Yeon Go (Researcher), Mi Hyun Hong (Graduate student), Young-Eun Lee (Professor)

Received: October 13, 2020; Accepted: November 28, 2020

Abstract

This study was conducted to investigate the inhibitory effect of 70% ethanol extract of yacon leaf on the metabolic syndrome induced by a high fructose (HF) diet in male Sprague-Dawley (SD) white rats. Five-week-old rats were divided into four groups and the experiment was carried out for 8 weeks. AIN-76A diets were fed to the control group and 60% HF diet to the metabolic syndrome induced group. Yacon leaf extracts were orally administered to the two experimental groups from the 5th week of the HF diet. The HF diet increased body weight, blood pressure, epididymal fat weight and size, total cholesterol, triglyceride, LDL-C, insulin and aorta thickness of the rats, but yacon leaf extracts administration reduced these changes. These results suggest that yacon leaf has an excellent preventive effect on the metabolic syndrome by improving obesity, dyslipidemia and blood pressure induced by an HF diet in rats. Therefore, yacon leaf has the potential for use as an ingredient in novel health foods for the prevention of the metabolic syndrome in the future.

Keywords: yacon leaf, metabolic syndrome, obesity, dyslipidemia, hypertension

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Journal of the Korean Society of Food Science and Nutrition 2020; 49: 1301-1308https://doi.org/10.3746/jkfn.2020.49.12.1301